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International Journal of Oncology Sciences

Vol. 3, Issue 1, Part A (2021)

Rosai dorfman disease-A rare disease in India

Author(s):

Dr. Laxmi Singotia, Dr. Lalit Patel, Dr. Vedant Kumar Modi

Abstract:
A 27 year old male presented with complaint of painless cervical lymphadenopathy which was progressively increasing in size and low grade fever on and off since one and a half year. Bilateral Cervical and axillary lymphnodes were palpable. The lymphnodes were firm, mobile and painless. Liver was palpable, non-tender and smooth in consistency. Hematological parameters and ESR in this case were in normal range. FNAC was suggestive of Hodgkin’s lymphoma but immunohistochemistry showed S-100 protein expression and lesion demonstrated emperipolesis. Hence the diagnosis of RDD was made. Patient was initially non-compliant to medical advise and presented after 5 years with similar complaints. He was managed using Rituximab and Chemotherapy with cyclophosphamide and Adriamycin. Also, oral prednisolone 100 mg was started. The patient responded very well to treatment over a period of two weeks and showed no signs of recurrence after 12 months follow up.

Pages: 10-12  |  658 Views  269 Downloads

How to cite this article:
Dr. Laxmi Singotia, Dr. Lalit Patel, Dr. Vedant Kumar Modi. Rosai dorfman disease-A rare disease in India. Int. J. Oncol. Sci. 2021;3(1):10-12.
International Journal of Oncology Sciences

International Journal of Oncology Sciences